China encourages the production and use of advanced non- PVC infusion soft bag packaging products, but currently there are only 28 related production enterprises in the country, 35 production lines, the annual output is only 90 million bags, and the demand for nearly 3 billion infusion bags per year The difference is far away. This is the information that the reporter recently obtained from the Non- PVC Infusion Soft Bag Packaging Seminar organized by the China Food and Drug Administration's China Pharmaceutical International Exchange Center and the American Sealed Air Company. PVC (polyvinyl chloride) is the most common polymer used to make IV bag films because of its low cost. However, its disadvantage is that the phthalate DEHP contained in its plasticizer is suspected of causing cancer and damaging the reproductive system; long-term use can lead to the accumulation of harmful substances; when it is deeply buried and burned, it releases dioxin and affects surroundings. The non- PVC infusion soft packaging bag is a completely new international concept of closed intravenous infusion products. The developed countries have been in clinical application for more than ten years. In recent years, our country has also strengthened management in this area, including the relevant content of the "Pharmaceutical packaging materials container management approach ( "Interim") has been introduced. Li Dakui, chairman of the Pharmaceutical Association of the Chinese Pharmaceutical Association and director of the Department of Pharmacy at the Peking Union Medical College Hospital, pointed out that the clinical requirements for infusion containers are safety, ease of use, environmental protection, and economy. Union Medical College Hospital, the most common of glass infusion bottles and infusion bag PVC and non-PVC infusion bag in three different kinds of infusion containers 15 commonly used traditional Chinese medicines include insulin, isosorbide dinitrate, paclitaxel, Xiangdan injection like the Adsorption studies have shown that the safety of non- PVC infusion bags is best. Although the adsorption of medicinal glass bottles is very small, there are problems such as back-flow air pollution, difficulty in detecting cracks in the slits, and falling off of plug powder. Asia's largest manufacturer of non- PVC infusion packaging products, Yang Xizhong, general manager of Guangdong Shenzhou Pharmaceutical Co., Ltd. proposed at the seminar that the establishment of non- PVC infusion packaging industry associations, set up an information platform.
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