First of all, anti-counterfeiting technology is a cross-cutting discipline, involving optics, chemistry, physics, electromagnetism, computer technology, spectroscopy, printing technology, packaging technology and many other fields. Ink anti-counterfeiting technology is a kind of anti-counterfeiting technology widely used in the pharmaceutical packaging industry. This kind of anti-counterfeiting technology is mainly used to add special materials in the ordinary ink connecting material, through a special process to become a special printing ink technology. The features of this type of anti-counterfeiting technology are: simple implementation, low cost, good concealment, vivid colors, and easy inspection. At present, there are mainly anti-counterfeiting ink UV-activated fluorescent anti-counterfeit inks, magnetic anti-counterfeit inks, thermal anti-counterfeiting inks, sunlight anti-counterfeiting anti-counterfeit inks, optical variable security inks, pressure-sensitive anti-counterfeit inks, infrared security inks, anti-falsification anti-counterfeiting ink, anti-counterfeit ink, etc. . Ink printing anti-counterfeiting is an important part of the pharmaceutical packaging anti-counterfeiting technology. Experiments show that fluorescent anti-counterfeit inks with fluorescent pigments are well-tolerant to water, acid, and alcohol, and are now widely used in pharmaceutical packaging, especially in blister packaging. It is also commonly used in other pharmaceutical packaging such as pharmaceutical flexible packaging and pharmaceutical labels. It can be said that the fluorescent anti-counterfeiting ink is a kind of anti-counterfeit ink which is most widely used in the anti-counterfeiting of pharmaceutical packaging inks. Fluorescent inks are made by adding the corresponding visible fluorescent compound to the ink. Its anti-counterfeit feature is: Under the action of visible light and ultraviolet rays, printed matter can emit glittering fluorescence. Different formulations can get different fluorescent inks. If ultraviolet ray excitation visible fluorescent compounds (such as tristyryl derivatives, stilbene derivatives, tetrastyryl derivatives, etc.) are added to the ink, ultraviolet fluorescent ink is obtained, which can emit red, yellow and green under the irradiation of ultraviolet rays. Blue and other visible light. Infrared fluorescent ink can be obtained by adding a visible fluorescent compound having infrared excitation in the ink, and green visible light can be emitted under the irradiation of the infrared light. Fluorescent inks are invisible and visible. 1 Invisible fluorescent ink security: The material used is invisible fluorescent ink, the printing process is simple. The ink printed invisible patterns or text, under the irradiation of ultraviolet light, showing a clear and bright fluorescent pattern, colorful. The anti-counterfeiting detection is convenient, as long as there is a UV light source or a money detector. Since the invisible fluorescent ink is invisible or colorless, it is invisible to the naked eye during printing, that is, it does not have any tracking marks for machine identification. Therefore, it is difficult to overprint, but this kind of anti-counterfeit concealment is better and the anti-counterfeiting strength is stronger. At present, most of the domestic pharmaceutical packaging uses this kind of invisible fluorescent ink. 2 tangible fluorescent ink anti-counterfeiting: the material used is tangible fluorescent ink, the printing process is simple, accurate registration, the printing effect is the same as the ordinary ink printing effect, but under the ultraviolet light, the printed material shows abnormal light, at this time, can be distinguished Ordinary ink. The use of the fluorescent ink type is very important for the anti-counterfeiting effect of the packaging. If the selection is inaccurate or poor, the anti-counterfeiting effect may not be obvious or any anti-counterfeiting requirements may not be achieved at all, for example, according to color light color theory As well as the principle of light absorption, the medium wavelength light absorbs short wavelengths. The following is an analysis of the specific conditions of fluorescent inks in the actual product structure. As shown in Figure 1, if we add a colorless fluorescent blue ink to a full-filled gold-colored coating, first the fluorescent blue ink layer will show blue (B) light under the illumination of a UV lamp, and then the undercoat layer The bottom golden (Y) color light is mixed, and theoretically analyzed by the color light additive method, the yellow light and the blue light are mixed and then appear white light, that is, the yellow light and the blue light are mutually complementary, that is, the anti-counterfeiting effect is poor or certain. Under the circumstances, no anti-counterfeiting effect can be seen at all. From the light absorption theory, this is because the medium-long-wavelength golden light in the spectrum absorbs part of the blue short-wavelength light, so that the color that the blue light should present is not seen, as shown in FIG. 2 . Fluorescent red works well under the same conditions, as shown in Fig. 3, and Fig. 4 shows the effect of fluorescent red under standard light source irradiation. From this we can draw a conclusion that we must be cautious when choosing fluorescent anti-counterfeiting inks. When the general printing system has the ink that produces its complementary color light or there is ink with a longer wavelength than the color light of the selected fluorescent ink, Fluorescent ink is best not to use or use it can not achieve a certain degree of security. Therefore, in the production process of fluorescent anti-counterfeiting inks used in the pharmaceutical packaging industry, the selection of fluorescent inks for a variety of different printing primer materials in the printing system is particularly important. In addition, the use of fluorescent ink for the printing process requirements are also more stringent, due to the particularity of its ink system, generally in the use of the process we must pay attention to consider the following factors: 1 Since gravure printing is commonly used in drug packaging and printing processes, the choice of solvent in gravure printing is very important. Solvent is an important component of gravure ink. It has solubility and volatility. Its volatilization rate is an important factor in determining the drying speed and printing quality of volatile ink. Solvent evaporation rate is slow, and the reproducibility of the printed image is better, but if the evaporation rate is too slow, it will not completely volatilize on the printed matter, the fluorescent ink layer is prone to adhesion, resulting in blurred security image, dirty layout, Influencing the anti-counterfeiting effect and the overall appearance of the product; conversely, if the solvent in the ink volatilizes too quickly during the printing process, ink whitening, sticky rollers, etc. may occur, and hidden troubles in the back layer of the ink layer may be hidden, resulting in the back of the packaging material. Dirty, under the UV light can clearly see the bright color spots, so that consumers have unsanitary intuition, when serious may affect the next coating and composite processes. Due to various manufacturers' printing equipment, the operating environment is different, such as the speed of the printing press, the structure of the drying system, the characteristics of the printing materials, the indoor temperature and humidity, etc. must be considered, so the use of solvents in the printing process Take all factors into consideration. Generally, the dissolution parameters of the binder resin are compared. In combination with the above requirements, two or three different boiling point solvents are used in combination to achieve the expected complete anti-counterfeit effect pattern. 2 The proportion of fluorescent ink in the security printing plate is generally very small. It can be said that very few fluorescent inks can produce a large number of anti-counterfeiting products. Therefore, when producing fluorescent ink products, they should try to follow the amount specified in the order book. Reasonably calculate the demand for ink, fight for one-time use, or do not leave too much to cause unnecessary waste. General fluorescent ink products can not be repeatedly used for a long time, one is easy to get dirty, bring unnecessary layout unclean problem, and the second is to dilute the fluorescent pigment after long-term solvent flushing ink system, so that the fluorescent anti-counterfeiting effect is greatly reduced, even in the ultraviolet lamp The pattern or text under illumination also appears dimmed, failing to achieve the desired anti-counterfeiting effect. This is also very important for factories and companies considering economic benefits because fluorescent inks are expensive and more than ten times more expensive than ordinary inks.